Sly Cooper is the main character of the Sly Cooper series of games.

Luigi is Mario's younger brother and one of the characters featured in the Mario series of games. He is depicted as taller and thinner than Mario, as well as having a green shirt and blue overalls. His personality is usually shown as being cowardly, although he has also shown braveness.

Vaas Montenegro is the main antagonist in Far Cry 3.

Tappy is an NPC in Game Freak's HarmoKnight.

Tempo is the primary protagonist and player-character in Game Freak's HarmoKnight. 

Sunny is the daughter of Olga Gurlukovich from Metal Gear Solid 2 and the adopted daughter of Hal Emmerich. Kidnapped by the Patriots as a newborn, Sunny was injected with life-monitoring nanomachines programmed to kill Sunny should an operative fail or die in a mission.

Irisa is a scrappy young Irathient woman whose life revolves around her relationship with Joshua Nolan, the man who rescued her and raised her like a daughter.

Andrew Ryan is the founder of Rapture, the owner of Ryan Industries, and one of the main antagonists in the BioShock series. Although he only makes a very brief appearance in the game, he frequently communicates to players in the original BioShock via radio messages, and in BioShock 2 through tape recordings.

Morrigan Aensland is a character from the Darkstalkers series of games, with her first appearance being in Darkstalkers: The Night Warriors.

Bishop was asynthetic crew member aboard the USS Sulaco in 2179 when it was sent to LV-426's colony to investigate the loss of contact. The character appears in the films Aliens and, briefly, Alien 3, as well as the upcoming videogame Aliens: Colonial Marines, which takes place some time after Alien 3 on the series' timeline.

The Weighted Companion Cube is a special type of Storage Cube that appears in both Portal and Portal 2. It is identical to the regular Weighted Storage Cube in both games, except that it has a heart where the Aperture Science logo would be.

Etna is the leader of the Prinny squad and one of the few vassals who remains by Laharl's side after King Krichevskoy's death in Disgaea: Hour of Darkness. After reviving Laharl through interesting means, Etna accompanies Larhal on his quest to reclaim his throne. Although not trustworthy and manipulative, she becomes Laharl's closest vassal and joins him on the battlefield.