Sander Cohen is a poet, composer, sculptor and playwright ruling over Fort Frolic in BioShock. Like many of Rapture's citizens, Cohen was driven mad by ADAM addiction and sadistically uses the Splicers in his domain to kill and torture in an 'artistic' manner.
Although little is known of his early life, he eventually became colleagues with an Elgar Vankin and Mimi Tabor, converting them to the Andrew Ryan's philosophy of a coming utopia. As one of Ryan's most trusted supporters, Cohen was granted the honor of writing the Rapture anthem, "Rise, Rapture, Rise".
When Jack arrives in Fort Frolic, Cohen cuts off his radio contact with Ryan and Atlas, stranding him on the level by causing the Bathysphere to submerge.