Lysandra is a character from the God of War series of games.
She was a Spartan woman who would eventually become Kratos' wife. The two of them had a child together named Calliope. While Kratos may have had many women, he considered Lysandra to be his soul mate.
While Kratos was attacking a village of Athena's followers, he was in such a frenzy that he didn't notice that he had killed both Lysandra and Calliope. While he continually sought forgiveness for killing them both, it wasn't until his final battle with Zeus that he forgave himself for that action.
In games prior to God of War: Ascension, she was voiced by Gwendoline Yeo, while she is voiced by Jennifer Hale in Ascension.