Saltonstall is an elderly politician in Columbia, and is a member of the Founders political faction. Judging by the posters found around Columbia, he is running for councilman of Ward 6.
He appears to be insane as he is found speaking to a crowd of empty chairs about the "importance of preserving the purity of Columbia." However, when the protagonist grabs a weapon, it's clear that Saltonstall is more than he appears, as not only his eyes, face, and voice undergo an inhuman change, but his promotional button shifts into a symbol of the Soviet Union.
A moment afterward, he calls Charles to attack Booker and use Murder of Crows upon him. After DeWitt kills Charles, Saltonstall utilizes a Sky-Hook on the Sky-Line to escape from him.
Saltonstall was the first main antagonist revealed for BioShock Infinite. The importance he attaches to his chauvinist ideology makes him a politically charged enemy in the same vein as Andrew Ryan and Sofia Lamb in earlier BioShock games.