| Weapon name | Damage | Location |
| .32 pistol | 6 | Shop's and various other npc's |
| Wild Bill's sidearm | 10 | Wild Bill's sidearm can be found in the Steelyard, close to Wernher's Hideout, on the corpse of Wild Bill. |
| 10mm pistol | 9 | Shop's and various other npc's |
| colonel Autumns's 10mm pistol | 13 | This weapon is carried by Augustus Autumn during the main story. During the Waters of Life quest after Colonel Autumn dies, you can grab his belongings as long as he falls near the door. |
| Silenced 10mm pistol | 8 | Shop's and various other npc's |
| Chinese pistol | 4 | Shop's and various other npc's |
| Zhu-Rong v418 Chinese pistol | 4 + 2 (for 5s) | The Zhu-Rong pistol can only be found in L.O.B. Enterprises |
| Dart gun | 6 + 8 (for 8s) | The dart gun is a player-crafted weapon |
| Scoped .44 magnum | 35 | Shop's and various other npc's |
| Blackhawk | 55 | Complete agatha's song to get it as a reward |
| Callahan's manum | 65 | If you choose to destroy the brotherhood of steel in borken steel addon you will find it in a safe in the reckage of the citadel |
| Paulson's revolver | 45 | Pick pocketing paulson |
| Assault rifle | 8 | Shop's and various other npc's |
| Infiltrator | 7 | Obtained from killing the guards at the entrance of the pitt after the bridge. |
| Perforator | 10 | Everett will give you the Perforator when you hand in 90 steel ingots. |
| BB gun | 4 | Obtained when it's your birthday in the vault |
| Chinese assault rifle | 11 | Shop's and various other npc's |
| Xuanlong assault rifle | 12 | It is found on Prime's body in the diner near the Jury Street Metro Station. |
| Hunting rifle | 25 | Shop's and various other npc's |
| Ol' painless | 30 | Next to Dave's chair in his vault |
| Lever-action rifle | 40 | Found throughout point lookout |
| Lincolns repeater | 50 | Found in the museum of national history |
| Railway rifle | 30 | A player built weapon |
| Sniper rifle | 40 | Shop's and various other npc's |
| Reservist's rifle | 40 | This variation of the sniper rifle is used by the Drifter in Dickerson Tabernacle Chapel. |
| Victory rifle | 40 | The Victory Rifle is inside a locked (Very Hard) locker in the sniper shack |
| Blackwater rifle | 45 | The Backwater rifle is found on a shelf in the Chinese Intelligence Bunker. |
| Combat shotgun | 55 | Shop's and various other npc's |
| The Terrible shotgun | 80 | This gun is carried by Smiling Jack |
| Double-barrel shotgun | 85 | Found throughout poinlook out add-on |
| Sawed-off shotgun | 50 | Found throughout poinlook out add-on |
| The Kneecapper | 75 | It can be obtained from Ronald Laren who lives in Girdershade. |
| 10mm SMG | 7 | Shop's and various other npc's |
| Sydney's 10mm "Ultra" SMG | 9 | Obtianed from sydney inside the national archives |
| Drone cannon | 140 | Dropped by drones in mother ship zeta |
| Drone cannon Ex-B | 140 | In the weapons lab on mothership zeta |
| Flamer | 16/24 | Shop's and various other npc's |
| Burnmaster | 24 | This weapon can be found in Franklin Metro Utility |
| Rapid-torch flamer | 16/24 | The rapid-torch flamer is located in the Adams Storage Facility |
| Slo-burn flamer | 18/27 | The Slo-burn flamer can be found on the upper level of the southeast portion of Launch Platform Base |
| Gatling laser | 8 | Shop's and various other npc's |
| Precision Gatling laser | 8 | This Gatling laser can only be found during Who Dares Wins |
| Vengeance | 11 | Vengeance can be found in the Deathclaw Sanctuary |
| Heavy incinerator | 15/22.5 | Found in broken steel addon |
| Minigun | 5 | Shop's and various other npc's |
| Eugene | 7 | Can be obtained from completing the Reilly's Rangers |
| Rock-it Launcher | 50 | This is a player created weapon |
| Fat man | 1610 | Shop's and various other npc's |
| Experimental MIRV | 12800 | The player must complete the unmarked quest Keller Family Refuge |
| Missile launcher | 170 | Shop's and various other npc's |
| Miss launcher | 220 | Miss Launcher is located in a weapons storage room inside Fort Independence |
| Alien atomizer | 35 | Mothership zeta |
| Atomic pulverizer | 37 | Mothership zeta |
| Alien blaster | 100 | Mothership zeta |
| Captian's sidearm | 35 | Dropped by the captian on Mothership zeta |
| Firelance | 80/120 | The Firelance can only be obtained in the "Unidentified Flying Debris" random encounter |
| Laer pistol | 12 | Shop's and various other npc's |
| Colonel Autumns laser pistol | 10 | It is found on Colonel Autumn in the Jefferson Memorial Rotunda during the quest Take it Back!. |
| Protectron's Gaze | 24 | It is awarded after handing the AntAgonizer's armor to the Mechanist |
| Smuggler's end | 18 | It is Elder Lyons' personal weapon and is located in his private safe in the B-Ring of the Citadel |
| Mesmetron | 1 | The Mesmetron is given to you by Grouse, the Paradise Falls entrance guard |
| Microwave emitter | 60 | The microwave emitter is found in the reward vault at the end of the quest A Meeting of the Minds. |
| Plasma Pistol | 25 | Shop's and various other npc's |
| MPLX novasurge | 80 | The weapon is found in the cargo hold area of Mothership Zeta |
| Alien disintegrator | 65 | Found most places on Mothership Zeta |
| Destabilizer | 30 | This weapon is found in the weapons lab's shooting range, on mother ship zeta |
| Gauss rifle | 100 | Completing ading the outcasts weapons vault |
| Laser rifle | 23 | Shop's and various other npc's |
| Metal blaster | 55 | It can be obtained in The Pitt by bringing Everett 50 steel ingots during the quest, "Mill Worker". |
| Wazer Wifle | 28 | Obtianed from biwwy |
| Plasma rifle | 45 | Shop's and various other npc's |
| A3-23's plasma rifle | 50 | A3-21's plasma rifle is carried by Harkness |
| Tesla cannon | 120 | Tesla cannon can be acquired upon your initial arrival atAdams Air Force Base |
| Tri-beam laser rifle | 75 | Found on various npcs including supermuntant overlords |
| Bottlecap mine | 500 | A player made mine |
| Cryo mine | 1 | These mines can be obtained from Elliot Tercorien |
| Frag mine | 100 | Shop's and various other npc's |
| Plasma mine | 150 | Shop's and various other npc's |
| Pulse mine | 11 | Shop's and various other npc's |
| Cryo grenade | 1 | These grenades can be obtained from Elliot Tercorien |
| Frag grenade | 100 | Shop's and various other npc's |
| Nuka-grenade | 500 | A player made grenade |
| Plasma grenade | 150 | Shop's and various other npc's |
| Pulse grenade | 10 | Shop's and various other npc's |
| Auto axe | 35 | Found around the pit |
| Man opener | 35 | The weapon is found on a bed in the back of the Supply Plant in The Pitt Steelyard |
| Steel saw | 16 | A chance to loot this item occurs during the slave revolt: several slaves will die, and some may have this weapon on their bodies. |
| The mauler | 45 | It can be obtained from Everett during the quest Unsafe Working Conditions once 80 steel ingots have been handed in. |
| The dismemberer | 20 | This axe can be obtained by completing Plik's Safari. |
| Chinese officers sword | 25 | Shop's and various other npc's |
| Vampire's edge | 10 | The Vampire's Edge belongs to Vance, and can be found in a 'sword cabinet' |
| Jingwei's shocksword | 35 | After completing the Anchorage Reclamation simulation in Operation: Anchorage |
| Combat Knife | 7 | Shop's and various other npc's |
| Occam's razor | 10 | Found on Commander Jabsco at the Talon Company base in Fort Bannister. |
| Stabhappy | 10 | It is found on a raider in "The raid shack", a short distance east of Bethesda Ruins. |
| Trench knife | 7 | After completing the Anchorage Reclamation simulation in Operation: Anchorage |
| Ant's sting | 4 | eceived when you complete the mission The Superhuman Gambit |
| Ritual knife | 6 | The ritual knife is found in the caves beneath the Ritual Site |
| Slasher knife | 50 | The knife is obtained along with the Pint-Sized Slasher mask during the Tranquility Lane quest |
| Toy knife | 1 | The toy knife can be found south of Turtledove Detention Camp west of one of the yellow signs |
| Ripper | 30 | Shop's and various other npc's |
| Jack the ripper | 30 | Found in deathclaw sanctuary |
| Samuria's sword | 24 | Found on the samurai body on mothership zeta |
| Shishkebab | 35/53 | Player made weapon |
| Shovel | 12 | Found around point lookout |
| Fertilizer shovel | 15 | You can get it from the tribal Croatoa |
| Switchblade | 5 | Shop's and various other npc's |
| Butch's Toothpick | 10 | Butch will be carrying this unique switchblade during the Trouble on the Homefront quest. |
| Baseball bat | 9 | Shop's and various other npc's |
| Lead pipe | 9 | Shop's and various other npc's |
| Nail board | 8 | Shop's and various other npc's |
| Board of education | 12 | Found in the Clifftop Shacks inside the smaller of the two sheds, in the hand of a skeleton on the bed. |
| Police baton | 4 | Shop's and various other npc's |
| Pool cue | 3 | Shop's and various other npc's |
| The break | 6 | The Break is found on a pool table in the center of Paradise Falls |
| Repellent stick | 1 | Gained upon completing the mole rat portion of the Wasteland Survival Guide quest |
| Rolling pin | 3 | - unknown - |
| Shock baton | 20 | Found all of mothership zeta |
| Electro Suppressor | 25 | Enter the engine room during the generator-destruction phase of the main quest |
| Sledgehammer | 20 | Shop's and various other npc's |
| The tenderizer | 30 | Located in Anchorage Memorial in the utility room with the broken door |
| Super sledge | 25 | Shop's and various other npc's |
| Fawkes super sledge | 32 | Found from pickpockting fawkes |
| Tire iron | 6 | Shop's and various other npc's |
| Highwayman's friend | 10 | Sitting on a shelf in Dominic's and Machete's house in Canterbury Commons |
| Brass knuckles | 6 | Shop's and various other npc's |
| Steel knuckles | 9 | Steel knuckles can be obtained by turning in 30 steel ingots to Everett |
| Deathclaw gaunlet | 20 | Player made weapon |
| Power fist | 20 | Shop's and various other npc's |
| Fisto! | 25 | Fisto! can be found on the upper area of the derelict power plant right across from MDPL-13 Power Station |
| The shocker | 20 | Found on mothership zeta |
| Spiked knuckles | 9 | Shop's and various other npc's |
| Plunkett's valid points | 12 | Plunkett's Valid Points are dropped by Junders Plunkett who is found at the Arlington House in the Arlington Cemetery |
