While playing the game, press Up to display Niko's cell phone. Press Up again to access the keypad. Then, enter one of the following codes to activate the corresponding cheat function. Once a code has been entered correctly, a new "Cheats" menu option will be available on your phone, below "Options", where you can access the cheats without having to enter the phone number again.
Note: Do not save the game after enabling a code to avoid unforeseen problems. Enabling some cheats will prevent the indicated achievement(s) from being earned. You can usually only spawn one vehicle at a time. Any previously spawned vehicles will disappear. However, if you spawn a vehicle, save the game, and load again, you can spawn another one and your original will not disappear. You must have it in your parking space in front of a safehouse or it will be gone before you have a chance to spawn another.
Cheat | Code |
| Health & Weapons Give Niko health and weapons. | 482-555-0100 |
| Health & Armour Give Niko health and armour. Blocks the achievement "Finish Him." | 362-555-0100 |
| Weapons (Advanced) Baseball Bat, Grenades, Combat Pistol, Combat Shotgun, SMG, Carbine Rifle, Combat Sniper, RPG. | 486-555-0100 |
| Weapons (Poor) Knife, Molotovs, Pistol, Pump Shotgun, Micro SMG, Assault Rifle, Combat Sniper, RPG. | 486-555-0150 |
| Remove Wanted Level Remove any police wanted level. Blocks the achievement "Walked free." | 267-555-0100 |
| Raise Wanted Level Add one star to Niko's wanted level. | 267-555-0150 |
| Change Weather Select from eight different weather types. | 468-555-0100 |
| Spawn Annihilator Spawn an Annihilator helicopter in front of Niko. | 359-555-0100 |
| Spawn Jetmax Spawn a Jetmax boat in front of Niko. | 938-555-0100 |
| Spawn NRG-900 Spawn an NRG-900 bike in front of Niko. | 625-555-0100 |
| Spawn Sanchez Spawn a Sanchez bike in front of Niko. | 625-555-0150 |
| Spawn FIB Buffalo Spawn an FIB Buffalo in front of Niko. | 227-555-0100 |
| Spawn Comet Spawn a Comet in front of Niko. | 227-555-0175 |
| Spawn Turismo Spawn a Turismo in front of Niko. | 227-555-0147 |
| Spawn Cognoscenti Spawn a Cognoscenti in front of Niko. | 227-555-0142 |
| Spawn Super GT Spawn a Super GT in front of Niko. | 227-555-0168 |
