Henry was a survivor along with his younger brother Sam in The Last of Us. The outbreak occured when Henry was only a child in Hartford, while his younger brother was born seven years afterwards. After the military abandoned the quarantine zone in Hartford, Henry along with a group of survivors headed for Pittsburg, where they were attacked by Hunters.
While hiding from the Hunters in Pittsburg the brothers run into Joel and Ellie. The four wait for nightfall to escape the city full of Hunters and infected, but Sam becomes infected. Blaming Joel, Henry if forced to shoot his brother and then kills himself.
