Melvin "Big Smoke" Harris is a major character from Grand Theft Auto: San Andreas. He was a childhood friend of the Johnson family, as well as Ryder, likely being born and living in Ganton, Los Santos, before moving to Idlewood. He was a high ranking member of the Grove Street Families gang, eventually becoming Sean Johnson's right-hand man.

Big Smoke tends to quote the Bible many times, indicating that he might possibly be a religious man. He also likes to eat, evident of the fact that he ordered a good portion of a fast food restaurant's menu during one of the early missions in the game. Smoke wants to be remembered after his death, which he makes multiple references to in the game.

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