Beloit Asylum
You'll start out next to Dr. Connors. Go down the long hallway and climb up the wall to the vent (or Web Rush!). Open the vent and climb in. You'll climb across an empty room and drop into it. Once you have dropped in, look for the control room right in front of you. You have to climb up to the upper level on either side to get in. Climb up over the railing on the left side. Go into the room and take a right into the control room. As you go through the doorway, you'll pick up your first Magazine. In the next room, use the control console to free Connors.
All of the inmates will be set free and you'll have to stop the few that escaped into the large room below. Climb up through the ceiling that has been destroyed and through the hole at the top. This will bring you into that room and set you to overlook the enemies. In this room, you can get two achievements pretty easily. Before you start these, run around the room and get the attention of all of the inmates here. The first is to get a combo modifier of x42 or more. To do this, start using your Web Rush attack on the inmates. Just keep hammering that button and turn the camera to a new enemy as you rush towards your current target so that as soon as you have finished, you can start the next one. Usually, it's just enough to turn the camera towards the large group of inmates behind you.
The second achievement is for immobilizing six enemies at once. You don't have to immobolize them simultaneously, they simply have to be immobil at the same time. Just keep shooting your web shooters at them and move around a bit. Whenever an enemy is immobilized, you'll automatically target the next one. If you have trouble with this one, you can come back later after you've gotten the web shooter upgrades for speed and impact force which will make this a walk in the park. It is possible to do both of these achievements at the same time but if for some reason you can't (accidentally knockout too many enemies for instance) just reload the checkpoint to do the second achievement.
*Achievement: I'm on a Roll!
*Achievement: Keep it together.
When you've gotten both of these, take out the remaining enemies in the room with regular combat. If you have trouble with this then this really is the best place to practice too. This room will give you the basics of attacking and evading. Just keep trying until you get it.
At this point, you want to climb up to the upper level to the right of the control room. A door on this level should open or already be opened and a security guard will be standing there. Go into the room behind the guard and take a sharp left to find anotherMagazine. Go up the stairs to the next room where another group of inmates is harrassing an orderly.
Here, you'll learn to use the environment to your advantage. At the back of the room will be a large dumpster. Use Web Rush on it to pick it up and through it at the enemies nearby. This will immediately stun any enemy it hits. While they are all stunned on the ground, run around and hammer on the Web Shooter button to web them to the floor. It may take a little practice to get faster but it's easily possible to web all of the enemies before they get up.
After you've taken out the inmates in here plus the extra two that show up,, there are two collectibles to grab. The first is an Audio Evidenceon the upper floor by where you came in and the other is a Magazineon the lower floor just by the window through which you can see Dr. Connors.
Go into the next checkpoint and Connors will open up the door to the next area. Run through and you'll be confronted by a group of about four men in a long corridor. Here, I will tell you the secret to easy combat (even on Superhero). Rememeber how you used the Web Rush to build up your combo modifier earlier for the achievement? Well, after you hit x12 modifier (or lower if you've upgraded your ability), you will stun with almost every punch and can use your Signature move which will instantly take an enemy out of combat. So use the Web Rush until you get it high enough. You'll know you've hit that point when the modifier turns red. When that happens, stop the Web Rushing. Hit an enemy with a single attack and then push the Web Shooter button to instantly take him out of the fight. Do this to each enemy in succession to take them all out without a scratch. I'll dub this the Web Rush Combo Technique.
When the room is clear, you will notice a lever on the right wall about half way up the hall that is glowing a little. Go up to it, activate it and then enter Web Rush. The gate at the end of the hall will open but it won't stay open long enough to run through so Web Rush through the gate. You'll probably land on the wall and right next to you should be a vent that you can enter. Do so.
Crawl through the vent and in the next room, you'll find a man sitting on the floor and next to him will be another Magazine.Grab the magazine and go through the other vent in this room. You'll come out to a bathroom with a single man. You can attack him or not, that's really up to you but he does still give experience. Go into the next room and you'll see a couple of staff being attacked by some inmates. Go into the room and throw a vending machine at them. This should make short work of them. Clean up any stragglers and then jump over the desks blocking the next hallway.
Connors will let you through another gate here. In the next room with the dancing inmates, hang a hard right and you'll see a toppled bookcase resting on a wheelchair. There's actually a Magazine on the wheelchair so pick that up. Go into the next hallway which will be on fire. Web Rush up to the ceiling and crawl past the first set of desks that are on fire. Once past them, you'll see another set of desks that are on fire. Between these two sets of burning desks will be a section of ground with a Magazine.
Hop back up to the ceiling and continue on. You'll watch Blackcat be freed. Turn into the nearby hallway and you'll see a small hole in the wall near the top. This will NOT be a vent but simply a small hole.
Go through the hole to enter another large "room". In this room will be a group of enemies. There's a couple of environment pieces you can use here and then just use the Web Rush Combo Technique on these guys to make short work of them (and make some serious XPs). There's a couple of collectibles in here, make sure you grab those. There aretwo magazines in opposite corners of this room.
Go into the next room and you'll find Connors again. Turn left to find a vent. Go through the vent and on the other side, hop down to use the terminal there. This will unlock the gate and let Connors into the courtyard.
Go through the doorway behind you and go up the stairs. You'll have to climb up because part of the stairs are on fire. At the top will be a man with a gun. Before you fight him, turn right to see a hallway "blocked" by fire. It's not actually blocked and you can go over it. Do so to find the last Magazine. Head back and take out that gunman.
Head into the lower area of the courtyard to start a fight. There will be a few enemies down here but the important thing to remember is the gunmen. They won't reveal themselves immediately but as you fight enemies below, they will appear in windows in the four corners of the courtyard (though you started by taking one out). As soon as you see the red laser appear, activate Web Rush and use it to attack them. Hit them a couple of times to take them out and then head back down or take out the next gunman.
Fighting in the courtyard itself is actually very easy. There are statues all around the outside of the courtyard that you can throw around. There's far more than you could possibly need so just use one and web the stunned enemies. If any remain, use another statue and web the enemies. Rinse and repeat until they are all down. After that, you'll escape with Connors.
NYC
You'll be back in NYC and can (theoretically) explore some more if you'd like. However, with Dr. Connors on your back, you can't activate Web Rush so you might as well just head back to the apartment. When you do, you'll have a quick conversation. From the apartment, you can change your costume, talk to the doctor, use the map to replay missions and boss fights, or you can use the window to head back into the city. At this point, there's not a whole lot to do but once you beat the game, you'll be able to replay any part of the game and explore the city during the day, at night or during any of the other times during the course of the game as you choose.
