There are 49 achievements with a total of 1200 GS.
| Medal of Honor | 100 |
| Complete 1 Mass Effect Playthrough on any setting | |
| Medal of Heroism | 25 |
| Complete Feros | |
| Distinguished Service Medal | 25 |
| Complete Eden Prime | |
| Council Legion of Merit | 25 |
| Complete Virmire | |
| Honorarium of Corporate Service | 25 |
| Complete Noveria | |
| Long Service Medal | 25 |
| Complete 2 Mass Effect Playthroughs on any setting | |
| Distinguished Combat Medal | 25 |
| Complete 1 Mass Effect playthrough on the Hardcore difficulty setting. Do not change the setting. | |
| Medal of Valor | 50 |
| Complete 1 Mass Effect playthrough on the Insanity difficulty setting. Do not change the setting. | |
| Pistol Expert | 10 |
| Register 150 Pistol Kills | |
| Shotgun Expert | 15 |
| Register 150 Shotgun Kills | |
| Assault Rifle Expert | 15 |
| Register 150 Assault Rifle Kills | |
| Sniper Expert | 15 |
| Register 150 Sniper Rifle Kills | |
| Lift Mastery | 15 |
| Use biotic Lift 75 times | |
| Throw Mastery | 15 |
| Use biotic Throw 75 times | |
| Warp Mastery | 15 |
| Use biotic Warp 75 times | |
| Singularity Mastery | 15 |
| Use biotic Singularity 75 times | |
| Barrier Mastery | 15 |
| Use biotic Barrier 75 times | |
| Stasis Mastery | 15 |
| Use biotic Stasis 75 times | |
| Damping Specialist | 15 |
| Use Damping Field 75 times | |
| AI Hacking Specialist | 15 |
| Use AI Hacking 75 times | |
| Overload Specialist | 15 |
| Use Shield Overload 75 times | |
| Sabotage Specialist | 15 |
| Use Sabotage 75 times | |
| First Aid Specialist | 15 |
| Use medi-gel 150 times | |
| Neural Shock Specialist | 15 |
| Use Neural Shock 75 times | |
| Scholar | 25 |
| Find all primary Alien: Council Races, Extinct Races and Non-Council Races codex entries | |
| Completionist | 25 |
| Complete the majority of the game | |
| Tactician | 25 |
| Complete playthrough with shield damage greater than health damage | |
| Medal of Exploration | 50 |
| Land on an uncharted world | |
| Rich | 25 |
| Exceed 1,000,000 Credits | |
| Dog of War | 25 |
| Register 150 organic enemy kills | |
| Geth Hunter | 25 |
| Register 250 synthetic enemy kills | |
| Soldier Ally | 20 |
| Complete the majority of the game with the Alliance soldier squad member | |
| Sentinel Ally | 20 |
| Complete the majority of the game with the Alliance sentinel squad member | |
| Krogan Ally | 20 |
| Complete the majority of the game with the krogan squad member | |
| Turian Ally | 20 |
| Complete the majority of the game with the turian squad member | |
| Quarian Ally | 20 |
| Complete the majority of the game with the quarian squad member | |
| Asari Ally | 20 |
| Complete the majority of the game with the asari squad member | |
| Power Gamer | 20 |
| Reach 50th level with one character | |
| Extreme Power Gamer | 50 |
| Reach 60th level with one character | |
| Renegade | 15 |
| Accumulate 75% of total Renegade points | |
| Paragon | 15 |
| Accumulate 75% of total Paragon points | |
| Paramour | 10 |
| Complete any romance subplot | |
| Spectre Inductee | 15 |
| Become a Spectre | |
| Charismatic | 10 |
| Use Charm or Intimidate to resolve an impossible situation | |
| Search and Rescue | 10 |
| Locate Dr. T'soni in the Artemis Tau cluster | |
| DLC: Bring Down the Sky | |
| Cost: 400 MSP Achievements: 1 Points: 50 | |
| Colonial Savior | 50 |
| Complete the Bring Down the Sky mission. | |
| DLC: Pinnacle Station | |
| Cost: 400 MSP Achievements: 3 Points: 150 | |
| Undisputed | 50 |
| Complete Ahern's survival mission | |
| New Sheriff in Town | 50 |
| Take first place in any combat scenario on Pinnacle Station | |
| Best of the Best | 50 |
| Take first place in 12 combat scenarios on Pinnacle Station | |
