Below contains the list of upgrades that can be found in the Campaign mode only.
| Name | Auto Loader |
| Bonus | Fire your weapon without reloading. |
| Location | Clear Aloof Challenger mission on Casual or higher difficulty without using the Infinite Rocket Launcher or a Green Herb. |
| Name | Bind 1 |
| Bonus | Ups stopping power by 100%. |
| Location | Complete Dodge Master mission and dodge enemy attacks 20 times. |
| Name | Bind 2 |
| Bonus | Ups stopping power by 500%. |
| Location | In Episode 7, Scenario 2. After defeating Rachel, get the drop it in the Cargo Room. |
| Name | Burst 1 |
| Bonus | Fires 2 consecutive shots with one trigger pull. |
| Location | In Episode 3, Scenario 2. After obtaining the Helm Key, unlock the door to Guest Room 4 in the upper cabins area. Scan below the bed to find it in the hall with an elevator. |
| Name | Burst 2 |
| Bonus | Fires 2 consecutive shots with one trigger pull. |
| Location | In Episode 7, Scenario 1. Obtain the Veltro Keycard in Episode 6 and then return to the Hallway with Paintings in the Cafeteria area and unlock the safe. |
| Name | Burst 3 (Hell Mode Only) |
| Bonus | Fires 5 consecutive shots with one trigger pull. |
| Location | In Episode 1, Scenario 1. Find this lying on some crates near a vent in the first room that Jill enters. |
| Name | Burst 4 |
| Bonus | Fires 3 consecutive shots with one trigger pull. |
| Location | In Episode 7, Scenario 1. Knock out Rachel by damaging her in the Cafeteria area for this drop. |
| Name | Burst 5 (Hell Mode Only) |
| Bonus | Fires 3 consecutive shots with one trigger pull. |
| Location | In Episode 10, Scenario 2. Immediately after the cutscene where Parker falls from the catwalk bridge, turn around and scan the portion of the catwalk bridge to the left of Jill. |
| Name | Burst 6 |
| Bonus | Fires 3 consecutive shots with one trigger pull. |
| Location | In Episode 10, Scenario 1. While playing as Parker, defeat Rachel in the Cafeteria area. |
| Name | Charge Shot 1 |
| Bonus | You can perform a charge shot by holding down the fire button. Charge time is long, but firepower goes up. |
| Location | In Episode 4, Scenario 1. Turn on the water purifier in the control room of the Solarium in Episode 3 and then re-enter the Solarium in Episode 4. Check the gazebo counter on the other side of the pool. |
| Name | Charge Shot 2 |
| Bonus | You can perform a charge shot by holding down the fire button. Charge time is long, but firepower goes up. |
| Location | In Episode 9, Scenario 2. After the lab is flooded, swim to the north side of the outside portion of the pool. This is on the closed shutter nearby. |
| Name | Charge Shot 3 |
| Bonus | You can perform a charge shot by holding down the fire button. |
| Location | Complete the Casual cleared mission or Finish Casual difficulty. |
| Name | Charge Shot 4 (Hell Mode Only) |
| Bonus | You can perform a charge shot by holding down the fire button. Charge time is long, but firepower goes up. |
| Location | In Episode 3, Scenario 2. Enter the Solarium through the Grand Hall in Episode 3 and solve the puzzle to unlock the door to the Control Room to check the control panel near the back of the room. |
| Name | Critical 1 |
| Bonus | Ups critical hit rate by 30% |
| Location | In Episode 4, Scenario 1. In the Casino area, scan the area below the lamp in the VIP Room. |
| Name | Critical 2 (Hell Mode Only) |
| Bonus | Ups critical hit rate by 100%. |
| Location | In Episode 6, Scenario 2. After the boss fight with the Draghignazzo in the Observatory, go on the opposite side of the room near the elevator and scan the floor near the windows. |
| Name | Damage 1 |
| Bonus | Ups firepower by 10%. |
| Location | In Episode 2, Scenario 2. In the Storage Hallway where Parker and Jill break down an iron door to retrieve their weapons, check the top of a cabinet near the door. |
| Name | Damage 2 |
| Bonus | Ups firepower by 20%. |
| Location | In Episode 3, Scenario 2. Check the table in the Conference Room where the Helm Key is obtained. |
| Name | Damage 3 |
| Bonus | Ups firepower by 40%. |
| Location | In Episode 6, Scenario 2. Scan the middle portion of the floor near the windows in the Observatory. |
| Name | Damage 4 |
| Bonus | Ups firepower by 60%. |
| Location | In Episode 7, Scenario 1. Use the Veltro Keycard to unlock the safe on the wall in Conference Room in the Bridge area of the ship. |
| Name | Damage 5 |
| Bonus | Ups firepower by 80%. |
| Location | In Episode 10, Scenario 2. Immediately after the cutscene where Parker falls from the catwalk bridge, turn around and scan the portion of the catwalk bridge to the left of Jill. |
| Name | Damage 6 (Hell Mode Only) |
| Bonus | Ups firepower by 100%. |
| Location | In Episode 3, Scenario 2. After gaining the Helm Key in the Conference Room, use it to unlock the door to the Study in the Bridge corridor area. Scan the side of the table closest to the map on the wall inside. |
| Name | Damage 7 (Hell Mode Only) |
| Bonus | Ups firepower by 150%. |
| Location | In Episode 12, Scenario 1. Check the waterway as you move toward the middle power room. |
| Name | Daze 1 |
| Bonus | Ups power to put an enemy into a daze by 100%. |
| Location | In Episode 5, Scenario 2. Check the platform off to the right in the flooder lower portion of the Engine Room. |
| Name | Daze 2 |
| Bonus | Ups power to put an enemy into a daze by 200%. |
| Location | In Episode 7, Scenario 1. Use the Veltro Keycard to open the safe in the Guest Cabin near the Heliport. |
| Name | Daze 3 (Hell Mode Only) |
| Bonus | Ups power to put an enemy into a daze by 300%. |
| Location | In Episode 4, Scenario 1. Scan the yellow containers on the right side of the Detention Room. |
| Name | Edge Runner 1 |
| Bonus | Firepower goes up as your health goes down. Maximum change is 50%. |
| Location | In Episode 10, Scenario 2. Already attached to the Government handgun that Jill picks up. |
| Name | Edge Runner 2 |
| Bonus | Firepower goes up as your health goes down. Maximum change is 100%. |
| Location | Complete the Researcher mission and scan all enemies. |
| Name | Fire Rate 1 |
| Bonus | Ups firing rate by 15%. |
| Location | In Episode 2, Scenario 2. Scan the top of the cabinet in the small corridor near the bottom floor of the Dining Room. |
| Name | Fire Rate 2 |
| Bonus | Ups firing rate by 30%. |
| Location | In Episode 2, Scenario 2. In the Promenade area, before lifting the shutter, move down the stairs across from the shutter and check the table. |
| Name | Fire Rate 3 |
| Bonus | Ups firing rate by 60%. |
| Location | In Episode 8, Scenario 1. On top of the water tank inside the Maintenance Room. |
| Name | Fire Rate 4 |
| Bonus | Ups firing rate by 60%. |
| Location | In Episode 10, Scenario 2. While on the outside walkway of the Queen Zenobia when the ship tilts, two wooden crates slide by Jill and crash against the door to reveal this. |
| Name | Fire Rate 5 (Hell Mode Only) |
| Bonus | Ups firing rate by 150%. |
| Location | In Episode 6, Scenario 2. After fighting the Draghignazzo and getting the Veltro Keycard, go near the antenna controls and check portion of the walkway that sticks out. |
| Name | Infighter 1 |
| Bonus | Firepower goes up as your distance from the target closes in under 4 meters. Maximum change is 20%. |
| Location | In Episode 4, Scenario 1 or Episode 7, Scenario 1. Use the Iron Anchor Key to unlock the Captain's Dining Room off the Cafeteria area and check the small table inside. |
| Name | Infighter 2 |
| Bonus | Firepower goes up as your distance from the target closes in under 4 meters. Maximum change is 50%. |
| Location | In Episode 7, Scenario 2. The Scagdead drops this part after he is defeated in the Cargo Room. |
| Name | Infighter 3 |
| Bonus | Firepower goes up as your distance from the target closes in under 4 meters. Maximum change is 100%. |
| Location | In Episode 4, Scenario 1 or Episode 7, Scenario 1. Use the Iron Anchor Key to unlock the Captain's Dining Room off the Cafeteria area and scan the floor near the chair inside. |
| Name | Long Magazine 1 |
| Bonus | Ups capacity by 20%. |
| Location | In Episode 3, Scenario 2. Go to the bottom floor of the Grand Hall and check the flooe of a wall indention to the right of the doors that lead to the Promenade. |
| Name | Long Magazine 2 |
| Bonus | Ups capacity by 40%. |
| Location | Complete the Angry Fist mission and successfully land 10 fully charged melee attacks. |
| Name | Long Magazine 3 |
| Bonus | Ups capacity by 80%. |
| Location | In Episode 7, Scenario 2. While at the bow of the ship, scan the bottom portion of the UAV as soon as the section begins. |
| Name | Long Magazine 4 |
| Bonus | Ups capacity by 100%. |
| Location | In Episode 8, Scenario 3. After fighting the Scarmiglione, scan the floor off to the left to reveal in the Sterilization Room with this inside. |
| Name | Long Magazine 5 (Hell Mode Only) |
| Bonus | Ups capacity by 150%. |
| Location | In Episode 3, Scenario 2. Use the Helm Key to unlock the door in the elevator corridor in the Upper Cabins and scan the side of the left cabinet closest to the entrance door. |
| Name | Long Magazine 6 (Hell Mode Only) |
| Bonus | Ups capacity by 200%. |
| Location | In Episode 7, Scenario 2. This is only available in Episode 7 on top of a container near the side of the bottom floor with the ladder by it. |
| Name | Narrow 1 |
| Bonus | Shotgun's scatter range becomes narrower by -4 degrees. |
| Location | In Episode 8, Scenario 3. On a bench in the Locker Room, outside the Sterilization Rooms. |
