The Mastermind skill tree excels in situational control, meaning the player who invests in it will be able to adapt to many different situations. The first point spent in this skill tree will let the player place the Doctor Bag, which can be used to regain health.
Tier 1 | ||
| Bonus: Doctor Bag interaction speed increased | ||
| Cable Guy | Basic | Can cable tie hostages quicker |
| Ace | Your supply of cable ties increases | |
| Combat Medic | Basic | Revive a crew member and receive a damage bonus for a short time |
| Ace | Reviving a crew member gives them more health | |
| Endurance | Basic | Stamina is increased |
| Ace | Entire crew's stamina is increased | |
Tier 2 | ||
| Bonus: Stamina is increased for you and your crew | ||
| Inside Man | Basic | Asset costs in Job Overview menu is reduced |
| Ace | Special Inside Man assets are unlocked | |
| Fast Learner | Basic | Gain more experience for completing days and jobs |
| Ace | Your crew also gains more experience for completing days and jobs | |
| Leadership | Basic | Your crew and your pistol weapon stability is increased |
| Ace | Weapon recoils are lowered for you and your crew | |
Tier 3 | ||
| Bonus: Shout distance is increased | ||
| Smooth Talker | Basic | More convincing when interacting with a pager |
| Ace | When you mark special enemies, those ones take bonus damage | |
| Equilibrium | Basic | Reduces spread with pistols, as well as the time it takes when holstering/unholstering pistols |
| Ace | Rate of fire with pistols is increased | |
| Dominator | Basic | Can intimidate non-special enemies, with lesser-trained ones being easier |
| Ace | Power and range of intimidation is increased | |
Tier 4 | ||
| Bonus: Converted enemy gains more health and damage | ||
| Stockholm Syndrome | Basic | Civilians who are nearby may revive you if you interact with them |
| Ace | Civilians who revive you may give you ammo | |
| Combat Doctor | Basic | Can place an additional Doctor Bag (2 max) |
| Ace | Doctor Bags will have additional charges | |
| Joker | Basic | Non-special enemies who have surrendered may be converted to fight for your side |
| Ace | Converted enemy gains more health and deals more damage | |
Tier 5 | ||
| Bonus: Time to convert an enemy is reduced | ||
| Black Marketeer | Basic | Cost of all purchases is reduced |
| Ace | Cost of all purchases is farther reduced and selling items is more lucrative | |
| Gunslinger | Basic | Pistols reload faster |
| Ace | Deal more damage with pistols | |
| Kilmer | Basic | Reload speed with assault rifles is increased |
| Ace | Spread while moving and firing with assault rifles is reduced | |
Tier 6 | ||
| Bonus: Intimidation when you shout is increased, as well as cost to buy assets in load-out menu | ||
| Control Freak | Basic | Cannot kill civilians when you deal damage to them |
| Ace | Civilians stay intimidated longer | |
| Pistol Messiah | Basic | You will instantly revive when you kill an enemy with a pistol while downed. This only works one time until you get out of custody |
| Ace | You get three chances instead of one | |
| Inspire | Basic | You can revive crew members quicker |
| Ace | Crew members can be revived from a distance by shouting at them | |
