All notable characters from Black / White, including every Gym Leader, make at least a cameo appearance within this game, with those that are no longer Gym Leaders only appearing post-game.
The three rivals from the previous game, Cheren, Bianca and N take on somewhat different roles in the new game. Cheren has now become the Gym Leader of Aspertia City, Bianca has become Professor Juniper's assistant and N has disappeared, reappearing later in the game to aid the player and stop New Team Plasma.
Besides Cheren, two other trainers have become Gym Leaders. Roxie is the second Gym Leader found in the game. Her Poison-type Gym is located in Virbank City. Marlon is the final Gym Leader found in the game. His Water-type Gym is located in Humilau City. Iris also takes on a new role. She is no longer a Gym Leader but is now the Pokemon Champion.
New Team Plasma, replacing Old Team Plasma from Black / White Version, is now lead by Ghetsis, with Colress acting as the leader and Zinzolin being one of the notable members of the faction.
