Xbox 360 Achievements:
| New Kid | 10 | |
| Reach 10th level. | ||
| Up and Comer | 20 | |
| Reach 20th level. | ||
| The Boss | 30 | |
| Reach 30th level. | ||
| Ol' Buddy Ol' Pal | 10 | |
| Recruit any companion. | ||
| The Whole Gang's Here | 25 | |
| Recruit all companions. | ||
| Crafty | 15 | |
| Craft 20 items. | ||
| Mod Machine | 15 | |
| Install 20 weapon mods. | ||
| Walker of the Mojave | 10 | |
| Discover 50 locations. | ||
| Master of the Mojave | 25 | |
| Discover 125 locations. | ||
| Globe Trotter | 25 | |
| Discover all snow globes. | ||
| You Run Barter Town | 15 | |
| Sell 10,000 caps worth of goods. | ||
| Blast Mastery | 15 | |
| Cause 10,000 damage with Energy Weapons. | ||
| Love the Bomb | 15 | |
| Cause 10,000 damage with Explosives. | ||
| Lead Dealer | 15 | |
| Cause 10,000 damage with Guns. | ||
| No Tumbler Fumbler | 15 | |
| Pick 25 locks. | ||
| Stim-ply Amazing | 15 | |
| Heal 10,000 points of damage with Stimpaks. | ||
| New Vegas Samurai | 15 | |
| Cause 10,000 damage with Melee Weapons. | ||
| Jury Rigger | 15 | |
| Repair 30 items. | ||
| Hack the Mojave | 15 | |
| Hack 25 terminals. | ||
| Artful Pocketer | 15 | |
| Pick 50 pockets. | ||
| Outstanding Orator | 15 | |
| Make 50 Speech challenges. | ||
| Desert Survivalist | 15 | |
| Heal 10,000 points of damage with food. | ||
| Old-Tyme Brawler | 15 | |
| Cause 10,000 damage with Unarmed weapons. | ||
| Know When to Fold Them | 10 | |
| Win 3 games of Caravan. | ||
| One Armed Bandit | 10 | |
| Play 10 spins of Slots. | ||
| Little Wheel | 10 | |
| Play 10 spins of Roulette. | ||
| Double Down | 10 | |
| Play 10 hands of Blackjack. | ||
| Caravan Master | 30 | |
| Win 30 games of Caravan. | ||
| The Courier Who Broke the Bank | 30 | |
| Get banned from all the Strip's casinos. | ||
| Hardcore | 100 | |
| Play the game from start to finish in Hardcore Mode. | ||
| Ain't That a Kick in the Head | 10 | |
| Complete Ain't That a Kick in the Head. | ||
| They Went That-a-Way | 25 | |
| Complete They Went That-a-Way. | ||
| Ring-a-Ding-Ding | 25 | |
| Complete Ring-a-Ding-Ding. | ||
| The House Always Wins | 30 | |
| Complete The House Always Wins. | ||
| For the Republic | 30 | |
| Complete For the Republic. | ||
| Render Unto Caesar | 30 | |
| Complete Render Unto Caesar. | ||
| Wild Card | 30 | |
| Complete Wild Card. | ||
| All or Nothing | 15 | |
| Complete All or Nothing. | ||
| Veni, Vidi, Vici | 15 | |
| Complete Veni, Vidi, Vici. | ||
| Eureka! | 15 | |
| Complete Eureka! | ||
| No Gods, No Masters | 15 | |
| Complete No Gods, No Masters. | ||
| Come Fly With Me | 20 | |
| Complete Come Fly With Me. | ||
| Talent Pool | 20 | |
| Complete Talent Pool. | ||
| Return to Sender | 20 | |
| Complete Return to Sender. | ||
| Arizona Killer | 20 | |
| Complete Arizona Killer. | ||
| You'll Know It When It Happens | 20 | |
| Complete You'll Know It When It Happens. | ||
| G.I. Blues | 20 | |
| Complete G.I. Blues. | ||
| That Lucky Old Sun | 20 | |
| Complete That Lucky Old Sun. | ||
| Volare! | 20 | |
| Complete Volare! | ||
| The Legend of the Star | 20 | |
| Complete The Legend of the Star. | ||
| DLC: Dead Money | ||
| Cost: 800 MSP Achievements: 5 Points: 140 | ||
| Assemble Your Crew | 20 | |
| Recruit Dean Domino, Christine and Dog. | ||
| Cash Out | 30 | |
| Confront Father Elijah in the Sierra Madre's Vault. | ||
| Having a Ball | 20 | |
| Complete the Sierra Madre Gala Event. | ||
| Safety Deposit Box | 40 | |
| Trap Father Elijah in the Sierra Madre's Vault. | ||
| Sierra Souvenir Aficionado | 30 | |
| Collect 500 Sierra Madre Chips. | ||
| DLC: Honest Hearts | ||
| Cost: 800 MSP Achievements: 5 Points: 140 | ||
| May my Hand Forget its Skill | 40 | |
| Evacuate Zion. | ||
| In a Foreign Land | 20 | |
| Scout the Zion Valley for signs of the White Legs. | ||
| O Daughter of Babylon | 30 | |
| Crush the White Legs. | ||
| When We Remembered Zion | 20 | |
| Arrive at Zion. | ||
| Restore Our Fortunes | 30 | |
| Resupply Daniel and the Sorrows. | ||
| DLC: Old World Blues | ||
| Cost: 800 MSP Achievements: 5 Points: 125 | ||
| Cardiac Arrest! | 20 | |
| Recover X-13 cardiac regulator sneaky suit! | ||
| Making Friends | 30 | |
| Reactivate all of the Sink's robotic assistants. | ||
| Make Up Your Mind | 20 | |
| Make up your mind... about your brain. | ||
| Outsmarted | 35 | |
| Complete Old World Blues. | ||
| Spinal-Tapped! | 20 | |
| Recover X-8 vertebrae-pulse-de-sensitizer frequency! | ||
| DLC: Lonesome Road | ||
| Cost: 800 MSP Achievements: 5 Points: 125 | ||
| ED-Ecated | 20 | |
| Find all of ED-E's upgrades in the Divide. | ||
| Condemned to repeat it | 20 | |
| Decide the fate of all the Divide dwellers. | ||
| Hometown Hero | 30 | |
| Complete Lonesome Road. | ||
| Rocket's Red Glare | 25 | |
| Acquire all upgrades for the Divide's signature weapon. | ||
| Warhead Hunter | 30 | |
| Detonate all of the warheads in the Divide. | ||
| DLC: Gun Runners Arsenal | ||
| Cost: 320 MSP Achievements: 5 Points: 125 | ||
| Curios and Relics | 15 | |
| Cause 10,000 damage with unique Mojave Wasteland weapons. | ||
| Master of the Arsenal | 25 | |
| Cause 10,000 damage with Gun Runners' Arsenal (GRA) Weapons. | ||
| Up to the Challenge | 20 | |
| Complete any three Gun Runners' Arsenal (GRA) one star (*) Challenges. | ||
| Combat Veteran | 25 | |
| Complete any three Gun Runners' Arsenal (GRA) two star (**) Challenges. | ||
| Pros Only | 40 | |
| Complete any three Gun Runners' Arsenal (GRA) three star (***) Challenges | ||
