The first section of this mission is all traversal and Angel Lift/Boosting. Since it is fast paced and hard to explain, I will simply say that it is best to simply run between the Angel Lifts, since the ground may fall right where you are going to land if to land if you jump or boost when not needed. When you land you will have a fight on your hands.
| Wave 1 | Wave 2 | Wave 3 | |
| Normal Difficulties | Elite Stygian x5, Witch | Stygian x3, Death Knight | Dreamrunner |
| Enhanced Difficulties | Elite Stygian x2, Frost Knight x3, Witch | Stygian x2, Frost Knight | Dreamrunner x2 |
| Dante Must Die! | Elite Stygian x4, Frost Knight, Witch | Stygian x3, Hell Knight | Dreamrunner x2, Witch |
| The Witch will not appear straight away, so focus on the Elite Stygian until she appears. Once she does, use the Aquila to break her barrier and cause he to be stunned. You can focus on the finishing the Elite Stygian while she is unconcious and then finish her off at the end. | |||
| The second wave appears as you only have 30 seconds to enter the building. Start by attacking the easy targets to farm some points, but run for the entrance when time gets low. | |||
| The Dreamrunner is back for a real fight this time. Back up to force him to teleport and then use three Rebellion strikes followed by two Arbiter strikes and then an Arbiter launch to take him out quickly. If you want to be cautious, make him teleport over and over again to let you slowly dwindle his health away. | |||
Head to the Divinity Statue and turn left toward the elevator, but break the door with Arbiter first to get the Lost Soul #64 before you board the elevator. You are dropped on the 86th floor and follow Kat's directions to a quick fight with two Elite Stygian and a Ravager. After the fight enter the doorway nearby to enter the skybridge. After Vergil shuts down the lasers, continue to the east wing and a fight.
| Wave 1 | Wave 2 | |
| Normal Difficulties | Shielded Pathos x2, Dreamrunner | - |
| Enhanced Difficulties | Elite Stygian x3, Hell Knight x3 | Stygian x4, Dreamrunner x2 |
| Dante Must Die! | Elite Stygian x5, Frost Knight x2 | Hell Knight x2, Butcher |
After the fight, Air Lift upstairs and head right to fight two Rages, which you should know how to beat now. After the fight, check the side room blocks by an Eryx crystal wall and the other blocked with black blocks floating up (wait for the opening) and then head to the elevator that leads to the 105th floor.
Exit the elevator and turn right to find another area with the flying black blocks and wait for the opening to jump across and get the Lost Soul #65, Lost Soul #66, and the Gold Key #3. Head to the other side of the building for another fight.
| Wave 1 | Wave 2 | |
| Normal Difficulties | Eliter Stygian x4 | Stygian x4, Witch |
| Enhanced Difficulties | Ravager x2, Dreamrunner | Lesser Stygian x8 |
| Dante Must Die! | Lesser Stygian x6, Dreamrunner | - |
Continue down a hallway carefully and kill two Demonic Shards. Further on is two Ghost Rages that should pose no problem if you use Aquila to stun one constantly as you use Osiris to take out the other. After the fight, jump up on the structure nearby and Angel Lift to the next floor.
As you continue, be careful of the crushing wall and then enter the next room with holes in the floor. Make your way around the area, taking out the three Elite Stygian that attack and look for a small alley with two long holes and a small platform inbetween that leads to the stairwell. Taking the stairs up will lead you to the Lost Soul #67 and taking them all the way down will lead them to the Gold Door - Extreme Traversal.
When you are ready, use the Angel Lifts to get across the gap and then drop to floor 105 and fight the Lesser Stygian before getting the Small Devil Trigger Staron the conference table. Nearby you should see some angelic vines block the Lost Soul #68. Return to the main area and appraoch the closed elevator, which will open, and gather up the Lost Soul #69 and Lost Soul #70 inside. Now return to the upper level by using Angel Lift near the first of the three Lost Souls.
After the quick cutscene, wait for an opening in the laser beams to jump and Angel Boost through. The first two sets are straight forward, but the thrid set requires you to let yourself fall slightly before using Angel Boost. If you manage to make it through without getting hit be all 5 sets of lasers you will earn the trophy/achievement Now my coat's all charred. If you get hit, you can restart from the last checkpoint to earn this.
After the first three sets of lasers, you will encounter a fight with two Stygian and a Dreamrunner. The best strategy is to stay in the middle of the bridge and away from the lasers. Use Aquila on the Stygian and finish them before dealing with the Dreamrunner.
upon exiting the skybridge, turn left and get the Lost Soul #71 and then follow the other path to Vergil where you will get the weapon Kablooey. Upon exiting the elevator on the 154th floor, turn left and follow it all the way to the end and get the Lost Soul #72 before entering the skybridge.
Cross the breaking bridge and then check the room protected by angelic vines. Make sure to check the whole floor and open the Copper Door - Bait and Switchbefore hopping on the elevator. When you reach the top you'll have a fight on your hands.
| Wave 1 | Wave 2 | Wave 3 | |
| Normal Difficulties | Harpy x3, Tyrant | Dreamrunner | - |
| Enhanced Difficulties | Harpy x3, Tyrant x2 | Ghost Rage, Blood Rage | Hell Knight x3, Witch |
| Dante Must Die! | Harpy x6, Tyrant x2 | Ghost Rage, Blood Rage | Hell Knight x5, Witch |
After the fight, you'll have to run across the rotating debris. Angel Boost across the first two platforms and when it looks like there is nowhere to go, Angel Lift to a high walkway and then again to finish the level.
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