#1) The first Rune can be found right after you get your powers from The Outsider, upon visiting The Hound Pits for the first time. It is found on a small piece of land, along the shoreline. Use Blink to get from land to land, until you get to the Rune.
#2) After returning from finishing High Overseer Campbell, you will be asked to investigate some noises coming from the sewers underneath the building. Go down and you will run into two Weepers. The first Rune can be found behind a grating, underneath the water, at the end of the tunnel.
#3) After returning from finishing High Overseer Campbell, you will be asked to investigate some noises coming from the sewers underneath the building. Go down and you will run into two Weepers. This Rune can be found inside of the desk by the Weepers.
#4) Piero sells one in his Workshop for 500 coins after first arriving there. He only sells one and it can be bought at any time.
#5) If you finish the optional mission of dueling Lord Shaw during Lady Boyle's Last Party, then Pendleton will give you a Rune upon returning to The Hound Pits.
#6) If you dispatch Lady Boyle in a nonlethal manner during Lady Boyle's Last Party, then you will receive a Rune from a letter that is on the table next to Corvo's bed in his bedroom.
#7) After Lady Boyle's Last Party, speak to Callista who is sitting inside the pub, who tells you that Emily is hiding somewhere. Find her and Emily will give you a Rune.
